Capítulo 1770: Chapter 1774: How About… Let Give It a Try?
The Chen Cang Institute of New Drug Research in the Dongyang Provincial High-Tech Developnt Zone.
It’s been officially operational for several months now, and everyone is working hard in scientific research, hoping to conquer Parkinson’s disease soon.
Since Chen Cang proposed the commonalities between Alzheir’s and Parkinson’s diseases, the progress of the entire scientific research has accelerated significantly!
However, scientific research always creates an illusion for people!
Every breakthrough makes one feel it’s a historic step forward, thinking excellent results will be achieved.
Yet the result is… after every breakthrough, it’s suddenly discovered that the difficulty of the matter has increased!
To solve the problem, the factors to consider and learn and the subjects still need to be expanded!
Professor Zhang Mu is engaged in Alzheir’s research, so when Chen Cang suggested that the enzys of asparaginyl endopeptidase could modify tau protein to make it more adhesive and toxic.
Thus, drugs inhibiting AEP often show certain benefits in the treatnt of Alzheir’s disease animal models.
If this is the case, is there an enzy that can increase the toxicity of folded alpha-synuclein?
This issue is truly complex!
It’s even like finding a needle in a haystack.
No one can find an “enzy” in the complex organization that explains this substance promotes the pathological alpha-synuclein after folding?
This requires complex bioengineering to handle!
Tense and urgent discussions are held in the office.
Tethys frowned slightly and said, “The progress of enzy engineering is really too slow now. As of now, I have yet to receive an accurate response from Professor Kang Xiding!”
“Every ti I talk about collaboration, the other party is always looking for various reasons to evade.”
“Ah…”
Upon hearing such disappointnt from Tethys, everyone was at a loss on how to console him.
Kang Xiding and Tethys used to be very good partners.
But since Tethys ca to China, his reputation within a certain circle beca akin to being shunned, and everyone avoided him.
Frankly, scientific research is mostly divided by national borders.
Even if many people are unwilling to admit it, they would find various reasons to persuade themselves and others.
Just like now, Chen Cang is indeed the fastest in Parkinson’s research progress, but why are those skilled experts unwilling to join?
Is it because they’re too naive to understand?
Of course not!
Being formidable doesn’t an everyone will join you.
The harsh reality is that scientific research is always like a competitive relationship.
Unless research results are produced, regardless of how ahead you are, it does not count as success!
Just like now, the institute needs experts in enzy engineering.
But it’s really difficult to find such top experts!
Few of Tethys’s forr partners are willing to co now!
Moreover, dostic bioengineering is just in the beginning stages, and research on protein enzys is truly struggling.
Even for the simplest enzy separation and purification, outdated bio-mbrane separation technology from five years ago in the United States is still being used.
These are basic research!
And yet, these basic studies determine the superstructure.
No scientific research occurs from thin air.
Zhang Mu, as the person in charge, couldn’t help but sigh.
The developnt of dostic pharmaceuticals is not rely lagging behind in pharmaceutical technology but because dical developnt is a comprehensive discipline!
dicine is not a simple subject; it’s a high-tech discipline.
It involves physics, chemistry, molecular biology… and many other fundantal disciplines!
Even the separation and purification of enzy engineering in one direction are extrely difficult at the mont!
Suddenly, everyone beca quiet.
Yang Lan couldn’t help but say, “Why don’t we find old friends at the Academy of Sciences?”
Zhang Mu shook his head, “He and Yu Shuangyong have similar technical skills, no need to look, even if found the effect wouldn’t be evident.”
Yu Shuangyong turned red listening.
Although Zhang Mu’s words were sowhat blunt, they were indeed the truth!
Finding the key core from the small enzy fragntation and separation is problematic!
Just then, the sound of a door opening halted abruptly.
Those lost in thought suddenly froze, so even startled, and montarily everyone was a bit displeased!
Who would co here during eting ti?
As everyone turned, they found it was Chen Cang!
Everyone breathed a sigh of relief.
Seeing the atmosphere was sowhat oppressive, Chen Cang couldn’t help but freeze: “What’s wrong… is this?”
“Why this oppressive atmosphere?”
Upon hearing this, everyone sighed.
And Zhang Mu directly said, “Professor Chen, we were just about to find you, sit down and talk.”
Chen Cang nodded, found a seat, and looked at Zhang Mu, “What happened?”
Zhang Mu said to Yu Shuangyong, “Old Yu, you explain, please.”
Yu Shuangyong nodded, picked up the data in his hand:
“Here’s the situation, we extracted, separated, and purified enzys within the rat nervous system, aiming to conduct research based on your initial idea, Professor Chen.”
“Asparaginyl endopeptidase can modify tau protein, making it more toxic and adhesive, just as you ntioned. Parkinson’s disease, as the neurodegenerative disorder second only to Alzheir’s in incidence, we also started separating and purifying enzys in Parkinson’s rats.”
“But… we seem to have encountered so issues, unsure if it’s due to technical reasons or other causes. In this month, we conducted over 600 separations, more than 3,000 tests, and tens of thousands of checks, without finding an enzy that could increase toxicity in folded alpha-synuclein!”
“These are the specific data. The enzys we can identify are only 671 types, and we can’t proceed further!”
After Yu Shuangyong finished, everyone sighed.
Tethys couldn’t help but say, “I reached out to my forr friend Professor Kang Xiding, but… the other party seems unwilling to help us!”
Zhang Mu suddenly suggested, “Professor Chen, why don’t we change direction?”
Everyone nodded in agreent.
Since learning asparaginyl endopeptidase from Alzheir’s disease hasn’t made a breakthrough in enzy engineering, perhaps we should switch directions?
After all… enzy engineering truly burns money.
This month, Zhang Mu tallied nearly 30 million yuan spent in this field, achieving nothing, wasted!
That’s scientific research, brutal and real!
As everyone felt a bit down.
Chen Cang suddenly said, “Why don’t… I give it a try?”
As these words ca out, everyone around suddenly beca quiet.
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